Cardiac arrest & resuscitation
Incidence, risk factors, and impact of post-return of spontaneous circulation events in patients with out-of-hospital cardiac arrest: A population-based study in Tokyo, Japan
Authors' conclusion
This study revealed population-based incidence and risk factors of post-ROSC events. Rearrest was common, leading to unfavourable neurological outcome; however, its deleterious impact may be mitigated by successful resuscitation efforts.
Study context
- Population
- Patients with out-of-hospital cardiac arrest (OHCA) and prehospital return of spontaneous circulation (ROSC), Tokyo, 2018–2022of 64,000 OHCA
- Participants
- 6,190 patients
- Exposure
- No rearrest vs Solved rearrest vs Unsolved rearrest
- Outcome
- Incidence and risk factors of post-ROSC events (rearrest and reattainment of ROSC) and their impact on favourable neurological outcome (CPC 1 or 2)
- Follow-up
- 1 month
Methodological detailsregistry (Tokyo Fire Department database), multivariable logistic regression, Data from Tokyo Fire Department database, 1 January 2018 to 31 December 2022
- Registry (Tokyo Fire Department database)
- Multivariable logistic regression
- Data from Tokyo Fire Department database, 1 January 2018 to 31 December 2022
Main finding
As reported in the abstract
Post-ROSC events and 1-month favourable neurological outcome
P < 0.001
- Rearrest incidence among patients with ROSC
- 28.4%
- ROSC reattainment among patients with rearrest
- 34.5%
Observational data: associations, not effects.
Original publication
Incidence, risk factors, and impact of post-return of spontaneous circulation events in patients with out-of-hospital cardiac arrest: A population-based study in Tokyo, Japan. Resuscitation. Published 6 July 2024. doi:10.
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