Pediatric anesthesia & critical care

Incidences and outcomes of intra-operative vs. postoperative paediatric cardiac arrest: A retrospective cohort study of 42 776 anaesthetics in children who underwent noncardiac surgery in a Thai tertiary care hospital

Eur J AnaesthesiolPublished Retrospective cohort study

Authors' conclusion

Postoperative cardiac arrest resulted in a higher mortality rate than intra-operative cardiac arrest.

Study context

Population
Paediatric patients aged 0 to 17 years undergoing anaesthesia for noncardiac surgery, tertiary care centre in Thailand, 2014 to 2019
Participants
42,776 anaesthetics
Exposure
Intra-operative vs postoperative paediatric cardiac arrest
  • Intra-operativen = 41reference
  • Postoperativen = 22
Outcome
Mortality rates
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Mortality after cardiac arrest

P = 0.001

Observational data: associations, not effects.

Further findings

Risk factors for mortality (multivariate analysis)

aOR (95% CI)
Emergency status5.388 (1.031–28.160)
Duration of CPR1.067 (1.016–1.120)
Time of postoperative cardiac arrest after anaesthesia completion
3.84 · median · range 0.05–19.47 · h

Incidence of paediatric perioperative cardiac arrest (PPOCA) and mortality (all anaesthetics)

PPOCA incidence per 10 000 anaesthetics
14.7 (95% CI 11.5 to 18.8)
Mortality per 10 000 anaesthetics
5.4 (95% CI 3.6 to 8.1)
Deaths among 63 PPOCAs
23 (36.5%)

Original publication

Incidences and outcomes of intra-operative vs. postoperative paediatric cardiac arrest: A retrospective cohort study of 42 776 anaesthetics in children who underwent noncardiac surgery in a Thai tertiary care hospital. Eur J Anaesthesiol. Published 15 May 2023. doi:10.1097/eja.0000000000001848

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