Pediatric anesthesia & critical care
Relationship between intra-operative urine output and postoperative acute kidney injury in paediatric cardiac surgery: A retrospective observational study
Main finding · Postoperative AKI and intra-operative UOResult — go to the resultAdjusted odds ratio 0.971 95% CI 0.930–1.014Authors' conclusion
Intra-operative UO was not associated with postoperative AKI during paediatric cardiac surgery. However, we found a significant association between UO and postoperative moderate-to-severe AKI.
Study context
- Population
- Children aged >28 days and <6 years undergoing cardiac surgery at Fuwai Hospital, 1 April 2022 to 30 August 2022
- Participants
- 1,184 children
- Exposure
- Acute kidney injury (AKI) vs non-AKI
- Outcome
- AKI by highest serum creatinine using KDIGO criteria
- Follow-up
- Within postoperative 7 days
Methodological detailssingle-centre
- Single-centre
Main finding
Postoperative AKI and intra-operative UO
Adjusted odds ratio
0.971
95% CI 0.930–1.014
P = 0.182
By group
AKI
2.6
median · IQR 1.4–5.4
non-AKI
2.7
median · IQR 1.4–4.9
Intra-operative UO
adjusted OR 0.971 (95% CI 0.930–1.014); P = 0.182
As reported in the abstract
- AKI incidence
- 23.1% (273/1184)
- Stage 1
- 17.7% (209/1184)
- Stage 2
- 4.2% (50/1184)
- Stage 3
- 1.2%, 14/1184
Observational data: associations, not effects.
Further findings
Postoperative moderate-to-severe AKI and intra-operative urine output (UO)
| Adjusted OR (95% CI) | P value | ||
|---|---|---|---|
| Intra-operative UO | 0.914 (0.838–0.998) | P = 0.046 | |
| 0.512Adjusted odds ratio (log scale) |
Original publication
Relationship between intra-operative urine output and postoperative acute kidney injury in paediatric cardiac surgery: A retrospective observational study. Eur J Anaesthesiol. Published 16 August 2024. doi:10.
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