Cardiac arrest & resuscitation

Increased rate of anoxic brain damage with laryngeal tube compared to endotracheal intubation in patients with shockable out-of-hospital cardiac arrest – Experience from the HAnnover COoling REgistry (HACORE)

ResuscitationPublished Registry-based cohort study

Authors' conclusion

In this cohort, use of LT was associated with a higher rate of anoxic brain damage and worse functional neurological outcome compared to use of ETI.

Study context

Population
Out-of-hospital cardiac arrest (OHCA) patients with shockable rhythms and ROSC prior to transport, HAnnover COoling REgistry (HACORE), treated by the Hannover Cardiac Resuscitation Algorithm incl. therapeutic hypothermia
Participants
452 patients
Exposure
Laryngeal tube vs endotracheal intubation for primary airway management
  • Endotracheal intubation (ETI)n = 405reference
  • Laryngeal tube (LT)n = 47
Outcome
Anoxic brain damage
Methodological detailsreal-world registry
  • Real-world registry

Main finding

As reported in the abstract

P = 0.011

Observational data: associations, not effects.

Further findings

Mortality

P = 0.487

Good neurological outcome (cerebral performance category 1&2) among survivors

P = 0.013

Safety

Pneumonia

P < 0.001

Original publication

Increased rate of anoxic brain damage with laryngeal tube compared to endotracheal intubation in patients with shockable out-of-hospital cardiac arrest – Experience from the HAnnover COoling REgistry (HACORE). Resuscitation. Published 20 October 2024. doi:10.1016/j.resuscitation.2024.110416

Composed by AI from the published abstract and checked against it. How Briefs are made →

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