Cardiothoracic & vascular anesthesia
Independent External Validation of a Preoperative Prediction Model for Delirium After Cardiac Surgery: A Prospective Observational Cohort Study
Authors' conclusion
The evaluated predictive model for delirium after cardiac surgery in this patient cohort showed only poor discriminative capacity but fair calibration.
Study context
- Population
- Adults ≥60 years undergoing elective cardiac surgery (CABG, mitral or aortic valve replacement or repair, combined procedures), 2 academic hospitals in Switzerland, 2018–2022
- Participants
- 348 adults
- Exposure
- 0 points vs 1 point vs 2 points vs ≥3 points
- Outcome
- Incidence of POD in the intensive or intermediate care unit (Intensive Care Delirium Screening Checklist)
Methodological detailsexternal validation of a prediction model, two-centre
- External validation of a prediction model
- Two-centre
Main finding
As reported in the abstract
POD incidence and model discrimination
- Overall postoperative delirium (POD) incidence
- 60 (17.4%)
- Pooled AUC
- 0.60 (median CI 0.525-0.679)
Observational data: associations, not effects.
Original publication
Independent External Validation of a Preoperative Prediction Model for Delirium After Cardiac Surgery: A Prospective Observational Cohort Study. J Cardiothorac Vasc Anesth. Published 6 December 2022. doi:10.
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