Respiratory failure & ventilation

Individualised Positive End‐Expiratory Pressure During Robotic‐Assisted Radical Prostatectomy Guided by Intratidal Compliance–Volume Curve Analysis

Acta Anaesthesiol ScandPublished Prospective interventional study

Main finding · Share of dorsal ventilationResult — go to the resultIncrease 41%

Authors' conclusion

Individualised PEEP guided by intratidal compliance-volume curve analysis enhanced dorsal lung ventilation, reduced driving pressure, and improved oxygenation during robotic-assisted prostatectomy.

Study context

Population
Male patients undergoing robotic-assisted prostatectomy
Participants
30 patients
Exposure
Individualised best positive end-expiratory pressure (PEEP) vs PEEP 7 cmH2O
Outcome
Share of dorsal lung ventilation
Methodological detailswithin-patient comparison, stepwise PEEP titration
  • Within-patient comparison
  • Stepwise PEEP titration

Main finding

Share of dorsal ventilation

Increase

41%

P < 0.001

As reported in the abstract

Observational data: associations, not effects.

Secondary outcomes

Oxygenation (PaO2/FiO2)

P = 0.016

Best PEEP level
20.6 · ± 2.7 · cmH2O

Safety

OutcomeP value
Norepinephrine dosage (slight increase); other haemodynamic parameters not affected by PEEPP = 0.01

Norepinephrine dosage (slight increase); other haemodynamic parameters not affected by PEEP

Haemodynamic parameters other than norepinephrine dosage not affected by PEEP

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Individualised Positive End‐Expiratory Pressure During Robotic‐Assisted Radical Prostatectomy Guided by Intratidal Compliance–Volume Curve Analysis. Acta Anaesthesiol Scand. Published 4 June 2025. doi:10.1111/aas.70067

Composed by AI from the published abstract and checked against it. How Briefs are made →

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