Respiratory failure & ventilation
Individualised Positive End‐Expiratory Pressure During Robotic‐Assisted Radical Prostatectomy Guided by Intratidal Compliance–Volume Curve Analysis
Main finding · Share of dorsal ventilationResult — go to the resultIncrease 41%Authors' conclusion
Individualised PEEP guided by intratidal compliance-volume curve analysis enhanced dorsal lung ventilation, reduced driving pressure, and improved oxygenation during robotic-assisted prostatectomy.
Study context
- Population
- Male patients undergoing robotic-assisted prostatectomy
- Participants
- 30 patients
- Exposure
- Individualised best positive end-expiratory pressure (PEEP) vs PEEP 7 cmH2O
- Outcome
- Share of dorsal lung ventilation
Methodological detailswithin-patient comparison, stepwise PEEP titration
- Within-patient comparison
- Stepwise PEEP titration
Main finding
Share of dorsal ventilation
Increase
41%
P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
Oxygenation (PaO2/FiO2)
P = 0.016
- Best PEEP level
- 20.6 · ± 2.7 · cmH2O
Safety
| Outcome | P value |
|---|---|
| Norepinephrine dosage (slight increase); other haemodynamic parameters not affected by PEEP | P = 0.01 |
Norepinephrine dosage (slight increase); other haemodynamic parameters not affected by PEEP
- Haemodynamic parameters other than norepinephrine dosage not affected by PEEP
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Individualised Positive End‐Expiratory Pressure During Robotic‐Assisted Radical Prostatectomy Guided by Intratidal Compliance–Volume Curve Analysis. Acta Anaesthesiol Scand. Published 4 June 2025. doi:10. 1111/ aas. 70067
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