Pediatric anesthesia & critical care
Infants Admitted to US Intensive Care Units for Respiratory Syncytial Virus (RSV) Infection During the 2022 Seasonal Peak
An erratum to this article was published (JAMA Netw Open, 1 Jul 2024 ↗)
Authors' conclusion
In this cross-sectional study, most US infants who required intensive care for RSV LRTIs were young, healthy, and born at term.
Study context
- Population
- Infants admitted ≥24 h to a unit providing intensive care for laboratory-confirmed RSV infection, 39 US pediatric hospitals in 27 states, October 17–December 16, 2022
- Participants
- 600 infants · 39 hospitals
- Outcome
- Characteristics and outcomes of RSV-related critical illness, incl. noninvasive respiratory support, invasive mechanical ventilation, vasopressors or ECMO, and death
Methodological detailspublic health prospective surveillance registry, multicentre
- Public health prospective surveillance registry
- Multicentre
Main finding
As reported in the abstract
Characteristics and respiratory support
- Age, median (IQR)
- 2.6 (1.4-6.0) months
- Male
- 361 (60.2%)
- Born prematurely
- 169 (28.9%)
- No underlying medical conditions
- 487 (81.2%)
- Admission for LRTI
- 594 [99.0%]
- Admission for apnea or bradycardia
- 77 [12.8%]
- Invasive mechanical ventilation
- 143 (23.8%)
- Duration of invasive mechanical ventilation, median [IQR]
- 6.0 [4.0-10.0] days
- Highest support in nonintubated: HFNC
- 243 [40.5%]
- Highest support in nonintubated: bilevel positive airway pressure
- 150 [25.0%]
- Highest support in nonintubated: CPAP
- 52 [8.7%]
- ECMO
- 4 (0.7%)
- Deaths
- 2
- LOS for survivors, median (IQR)
- 5 (4-10) days
Observational data: associations, not effects.
Further findings
Risk factors for intubation
- Age <3 months, prematurity (gestational age <37 weeks) or public insurance associated with higher risk for intubation
Original publication
Infants Admitted to US Intensive Care Units for RSV Infection During the 2022 Seasonal Peak. JAMA Netw Open. Published 1 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →