Hemodynamics, fluids & transfusion

Inferior vena cava ultrasound to predict hypotension after general anesthesia induction: a systematic review and meta-analysis of observational studies

Can J AnaesthPublished Systematic review and meta-analysis of observational studies

Authors' conclusion

Preoperative IVC-CI is a strong predictor of postinduction hypotension.

Study context

Population
Adults presenting for elective surgery under GA (excluding obstetric patients and studies exclusively in patients with obesity)
Participants
1,166 adults · 14 studies
Comparison
Inferior vena cava collapsibility index (IVC-CI) vs IVC-CI 40-45%
Outcome
Diagnostic accuracy of IVC-CI and dIVCmax in predicting postinduction hypotension
Methodological detailsdiagnostic accuracy, bivariate random effects model, GRADE
  • Diagnostic accuracy
  • Bivariate random effects model
  • GRADE

Pooled result

As reported in the abstract

Postinduction hypotension prediction
GroupSensitivitySpecificityHierarchical summary receiver-operating characteristic area under the curve (HSROC-AUC)
IVC-CI0.68 (95% CI 0.55 to 0.79; coverage probability 0.91)0.78 (95% CI 0.69 to 0.85; coverage probability 0.9)0.80 (95% CI 0.68 to 0.85)

IVC-CI

Sensitivity0.68 (95% CI 0.55 to 0.79; coverage probability 0.91)
Specificity0.78 (95% CI 0.69 to 0.85; coverage probability 0.9)
Hierarchical summary receiver-operating characteristic area under the curve (HSROC-AUC)0.80 (95% CI 0.68 to 0.85)

Further pooled results

OutcomeIVC-CI 40-45%
IVC-CI threshold range 40-45% (subgroup)High quality of evidence
HSROC-AUC0.86 (95% CI 0.69 to 0.93)

Original publication

Inferior vena cava ultrasound to predict hypotension after general anesthesia induction: a systematic review and meta-analysis of observational studies. Can J Anaesth. Published 3 July 2024. doi:10.1007/s12630-024-02776-4

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