Hemodynamics, fluids & transfusion
Prevention of hypotension after induction of general anesthesia using point-of-care ultrasound to guide fluid management: a randomized controlled trial
Errata to this article were published (Can J Anaesth, Sep 2024 ↗ · Oct 2024 ↗)
Primary result · Hypotension after induction of GA (GAIH)Result — go to the resultRelative risk 0.53 95% CI 0.32–0.89Authors' conclusion
A preoperative fluid bolus in patients with a collapsible IVC reduced the incidence of GAIH without associated adverse effects.
Study context
- Population
- Adults scheduled for elective noncardiac surgery under general anesthesia (GA) with a collapsible inferior vena cava (IVC) (IVC collapsibility index ≥ 43%) on preoperative point-of-care ultrasound scan (POCUS)
- Participants
- Forty adults
- Comparison
- Fluid bolus vs Control
- Fluid bolusn = 20
- Controln = 20reference
- Primary endpoint
- Hypotension after induction of GA (vasopressors/inotropes or MAP decrease < 65 mm Hg or > 25% from baseline)
- Follow-up
- Within 20 min of induction of GA
Methodological detailssingle-centre, blinded surgical and anesthesia teams
- Single-centre
- Blinded surgical and anesthesia teams
Primary result
Hypotension after induction of GA (GAIH)
Relative risk
0.53
95% CI 0.32–0.89
P = 0.02
Fluid bolus vs Control
RR 0.53 (95% CI 0.32–0.89); P = 0.02
As reported in the abstract
Further findings
- Time to complete POCUS, mean (SD) 4 (2) min
- Duration of fluid bolus administration, mean (SD) 14 (5) min
Safety
Surgical delays and adverse events from the study intervention
- Neither surgical delays nor adverse events occurred
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Prevention of hypotension after induction of general anesthesia using point-of-care ultrasound to guide fluid management: a randomized controlled trial. Can J Anaesth. Published 13 March 2024. doi:10.
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