Hemodynamics, fluids & transfusion
Influence of Right and Left Bundle Branch Block in Patients With Cardiogenic Shock and Cardiac Arrest
Main finding · 30-day all-cause mortalityResult — go to the resultHazard ratio 1.807 95% CI 1.107–2.947Authors' conclusion
Besides the Acute Physiology Score, lactate, and troponin levels, RBBB was associated with an increased 30-day all-cause mortality in consecutive CS patients with and without cardiac arrest, whereas LBBB showed no prognostic impact.
Study context
- Population
- Adults with cardiogenic shock (CS), ICU of a tertiary academic hospital in Germany
- Participants
- 248 adults
- Exposure
- Right bundle branch block (RBBB) vs left bundle branch block (LBBB) vs no bundle branch block (BBB)
- Outcome
- 30-day all-cause mortality
- Follow-up
- 30 days
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
Hazard ratio
1.807
95% CI 1.107–2.947
P = 0.018
By group
Observational data: associations, not effects.
Further findings
30-day all-cause mortality, CS with cardiac arrest at admission (subgroup) · 30 days — RBBB vs LBBB · three-group log-rank test (RBBB vs LBBB vs no BBB)
P = 0.008
Other predictors of 30-day all-cause mortality (multivariable Cox model)
| HR (95% CI) | P value | ||
|---|---|---|---|
| Lactate | 1.065 (1.018–1.115) | P = 0.006 | |
| Troponin I | 1.003 (1.001–1.005) | P = 0.001 | |
| Acute Physiology Score | 1.033 (1.001–1.066) | P = 0.041 | |
| 0.512Hazard ratio (log scale) |
Liver or severe renal failure
- No association of RBBB with incidence of liver or severe renal failure
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →