Pediatric anesthesia & critical care

Interrater Reliability of the 2015 Pediatric Acute Lung Injury Consensus Conference Criteria for Pediatric ARDS

ChestPublished Retrospective interrater reliability study

Authors' conclusion

The interrater reliability of the 2015 PALICC criteria for diagnosing moderate to severe PARDS in this cohort was substantial, with diagnostic disagreements commonly caused by differences in chest radiograph interpretations. Patients with cardiac disease or chronic respiratory failure were more vulnerable to diagnostic disagreements.

Study context

Population
Patients with acute hypoxic respiratory failure receiving invasive mechanical ventilation, admitted 2016–2021
Participants
191 encounters
Outcome
Interrater reliability (Gwet's agreement coefficient) of the 2015 Pediatric Acute Lung Injury Consensus Conference (PALICC) criteria for moderate to severe pediatric ARDS (PARDS)
Methodological detailsretrospective review by two PICU physicians
  • Retrospective review by two PICU physicians

Main finding

As reported in the abstract

Interrater reliability

Encounters with diagnostic disagreement

37

Gwet's agreement coefficient (substantial), 95% CI 0.65-0.83

0.74

Observational data: associations, not effects.

Further findings

Factors associated with disagreement

OR (95% CI)P value
Chronically ventilated4.66 (2.16–10.08)P < 0.001
Primary cardiac admission diagnosis3.36 (1.18–9.53)P = 0.02
Cardiothoracic surgery during admission4.90 (1.60–15.00)P = 0.005

Causes of disagreement

Different interpretations of chest radiographs
56.8%
Ambiguity in origin of pulmonary edema
37.8%
Unclear if current condition significantly different from baseline
27.0%

Reviewer diagnostic confidence

At least moderately confident
73%
Less likely to be confident with cardiac disease or chronic respiratory failure

Original publication

Interrater Reliability of the 2015 Pediatric Acute Lung Injury Consensus Conference Criteria for Pediatric ARDS. Chest. Published 14 April 2023. doi:10.1016/j.chest.2023.04.019

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