Prognostic Accuracy of the Phoenix Sepsis Criteria for Mortality in Children With Suspected Infection: A Systematic Review and Meta-Analysis
Pooled result · Prognostic accuracy for in-hospital mortalityResult — go to the resultDifference 0.10 95% CI 0.04–0.19Authors' conclusion
The PSC demonstrates good prognostic accuracy for mortality and outperforms the IPSCC criteria.
Study context
- Population
- Children younger than 18 years with suspected infection in hospital settings15 studies (16 cohorts), encounters
- Participants
- 2,601,038 participants
- Comparison
- Phoenix Sepsis Criteria (PSC) vs International Pediatric Sepsis Consensus Conference (IPSCC)
- Outcome
- Prognostic accuracy for in-hospital mortality
Methodological detailsQUADAS-2 quality assessment
- QUADAS-2 quality assessment
Pooled result
As reported in the abstract
Difference
0.10
95% CI 0.04–0.19
By group
PSC
- Pooled sensitivity
- 0.77 (95% CI, 0.67-0.85)
- Specificity
- 0.73 (95% CI, 0.51-0.87)
- Diagnostic odds ratio
- 9.2 (95% CI, 5.1-16.8)
- AUC
- 0.81 (95% CI, 0.75-0.84)
IPSCC
0.71
AUC
PSC vs IPSCC
difference 0.10 (95% CI 0.04–0.19)
Further pooled results
| Outcome | ICU | ED |
|---|---|---|
| PSC specificity by setting (subgroup) | 0.48 | 0.99 |
Original publication
Prognostic Accuracy of the Phoenix Sepsis Criteria for Mortality in Children With Suspected Infection: A Systematic Review and Meta-Analysis. Crit Care Med. Published 5 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →