Regional anesthesia

Intertransverse process block (ITPB) at the retro-superior costotransverse ligament (retro-SCTL) space: Evaluation of local anesthetic spread using MRI and sensory blockade in healthy volunteers

J Clin AnesthPublished Mechanistic study

Authors' conclusion

A single-injection medial retro-SCTL space block, at the T4-T5 level with 10.5 ml of local anesthetic, consistently spreads to the ipsilateral intercostal and paravertebral spaces, sympathetic chain, costotransverse space, neural foramina and epidural space, but produces ipsilateral sensory blockade that is variable and wider over the posterior than anterior hemithorax.

Study context

Population
Healthy volunteers receiving a medial retro-SCTL space block at T4-T5 (10 ml 0.5 % bupivacaine with 0.5 ml gadolinium)
Participants
10 volunteers
Outcome
Local anaesthetic spread (MRI) and sensory blockade
Methodological detailshealthy volunteers, single-injection, ultrasound-guided, MRI, MRI at 15 min; loss of sensation to cold at 15 and 60 min, then hourly for 5-h
  • Healthy volunteers
  • Single-injection
  • Ultrasound-guided
  • MRI
  • MRI at 15 min; loss of sensation to cold at 15 and 60 min, then hourly for 5-h

Main finding

As reported in the abstract

Median [IQR] dermatomes

3.5 [2-5] vs 0 [0-1.25]

P < 0.001

Hypoesthesia, anterior hemithorax vs Anesthesia, anterior hemithorax

Median [IQR] dermatomes

6[3-7] vs 2[1-3]

P < 0.001

Hypoesthesia, posterior hemithorax vs Anesthesia, posterior hemithorax

Median [IQR] dermatomes

2[1-3] vs 0[0-1.25]

P = 0.01

Anesthesia, posterior hemithorax vs Anesthesia, anterior hemithorax

Spread to intercostal and paravertebral spaces, sympathetic chain, costotransverse space, neural foramina and epidural space in all participants
100 %
Contralateral dermatomes affected
3 (30 %)

Further findings

Correlation of LA spread with ipsilateral dermatomes

Hypoesthetic dermatomes, r = 0.53
P = 0.11
Anesthetic dermatomes, r = 0.09
P = 0.78
No statistically significant correlation

Original publication

Intertransverse process block (ITPB) at the retro-superior costotransverse ligament (retro-SCTL) space: Evaluation of local anesthetic spread using MRI and sensory blockade in healthy volunteers. J Clin Anesth. Published 18 December 2024. doi:10.1016/j.jclinane.2024.111718

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