Neuroanesthesia & neurocritical care
Intracranial compliance monitoring using pulse shape index in traumatic brain injury: relation to cerebral physiology and clinical outcome
Authors' conclusion
PSI was linked to established indicators of intracranial compliance and provided early warning of impending intracranial hypertension. While PSI showed univariable associations with outcome, these did not remain in multivariable models.
Study context
- Population
- Traumatic brain injury (TBI) patients with ≥ 12 h of intracranial pressure (ICP)/pulse shape index (PSI) monitoring
- Participants
- 321 patients
- Outcome
- Relation of PSI (artificial intelligence (AI)-based ICP pulse shape index, 1 normal to 4 disturbed) to markers of intracranial compliance, risk of ICP crisis and clinical outcome
Main finding
As reported in the abstract
PSI during the preceding hour predicted increased ICP burden above 20 mmHg (marginal R2)
≈30%
Observational data: associations, not effects.
Original publication
Intracranial compliance monitoring using pulse shape index in traumatic brain injury: relation to cerebral physiology and clinical outcome. Crit Care. Published 9 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →