Neuroanesthesia & neurocritical care
Intraoperative clonidine in endometriosis and spine surgery: A protocol for two randomised, blinded, placebo‐controlled trials
Study context
- Population
- Patients scheduled for endometriosis surgery (CLONIPAIN) or undergoing spine surgery (CLONISPINE)planned per trial
- Participants
- 120 patients
- Planned comparison
- Single intraoperative intravenous (IV) clonidine vs placebo
- Primary endpoint
- Opioid consumption
- Follow-up
- First three postoperative hours
Methodological detailsblinded, placebo-controlled, two separate trials (CLONIPAIN, CLONISPINE), Planned sample size for 90% power at alpha 0.05
- Blinded
- Placebo-controlled
- Two separate trials (CLONIPAIN, CLONISPINE)
- Planned sample size for 90% power at alpha 0.05
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Intraoperative clonidine in endometriosis and spine surgery: A protocol for two randomised, blinded, placebo‐controlled trials. Acta Anaesthesiol Scand. Published 10 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →