Perioperative medicine & outcomes
Intraoperative electroencephalogram features related to frailty in older patients: an exploratory prospective observational study
Authors' conclusion
Frail patients had reduced EEG (0-30 Hz) power after the induction of propofol-based general anesthesia. After adjusting for age, CCI, and MMSE score, frail patients still showed evidence of reduced δ, θ, α, and β power.
Study context
- Population
- Older patients scheduled for elective spinal surgery or transurethral prostatectomy under propofol-based GAincluded in final analysis
- Participants
- 26 vs 20
- Comparison
- Frail vs robust older patients
- Frailn = 26
- Robustn = 20reference
- Primary endpoint
- Differences in baseline and intraoperative EEG characteristics (spectrogram and power spectra)
Methodological detailsDecember 2020 to November 2021
- December 2020 to November 2021
Primary result
As reported in the abstract
Intraoperative EEG spectral parameters
P = 0.002
Further findings
FRAIL score and intraoperative EEG power, adjusted for age, Charlson Comorbidity Index (CCI) and mini-mental state examination (MMSE) score
- FRAIL score still negatively associated with total, delta, theta, alpha and beta powers
Original publication
Intraoperative electroencephalogram features related to frailty in older patients: an exploratory prospective observational study. J Clin Monit Comput. Published 22 January 2024. doi:10.
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