Perioperative medicine & outcomes
The prevalence and trajectory of frailty in older surgical patients: A longitudinal multicentre cohort study
Authors' conclusion
The prevalence of preoperative prefrailty and frailty was high among older surgical patients. A high preoperative FRAIL score and severe functional disability were associated with greater odds of postoperative 180-day frailty.
Study context
- Population
- Non-cardiac surgical patients aged ≥65 years
- Participants
- 307 patients
- Exposure
- Robust vs Prefrail vs Frail
- Outcome
- Preoperative and postoperative prevalence of frailty (five-item FRAIL scale)
- Follow-up
- Preoperatively and at 30, 90, and 180 days
Methodological detailsmulticentre, longitudinal
- Multicentre
- Longitudinal
Main finding
As reported in the abstract
Preoperative frailty prevalence · preoperatively
Observational data: associations, not effects.
Further findings
Preoperative risk factors for 180-day frailty
| aOR (95% CI) | ||
|---|---|---|
| Preoperative frailty | 2.65 (1.51–4.97) | |
| Functional disability | 4.71 (1.41–15.65) | |
| 0.050.21520Adjusted odds ratio (log scale) |
Original publication
The prevalence and trajectory of frailty in older surgical patients: A longitudinal multicentre cohort study. Anaesth Crit Care Pain Med. Published 27 June 2025. doi:10.
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