Pediatric anesthesia & critical care
Intraoperative Hypotension in Children Undergoing Noncardiac Surgery: An Exploratory Single-Center Analysis of Incidence, Associated Risk Factors, and Outcomes
Authors' conclusion
Although brief intervals of IOH among children undergoing noncardiac procedures can occur, recognizing risk factors for IOH can identify high-risk patients preoperatively.
Study context
- Population
- Pediatric patients undergoing noncardiac surgery, single centre, January 2015–August 2022
- Participants
- 6,748 patients
- Outcome
- Incidence of IOH (SBP below −2 SD of age- and sex-specific reference values for ≥5 minutes)
Methodological detailssingle-centre, exploratory multivariable analysis, ACS NSQIP pediatric database
- Single-centre
- Exploratory multivariable analysis
- ACS NSQIP pediatric database
Main finding
As reported in the abstract
Incidence of IOH
Institution-specific incidence of intraoperative hypotension (IOH): 529/6748
7.8%
95% CI 7.2%–8.5%
Observational data: associations, not effects.
Further findings
Preoperative risk factors associated with IOH
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Respiratory diseaseExploratory multivariable analysis | 1.5 (1.1–2.05) | P = 0.01 | |
| ASA ≥ 3Exploratory multivariable analysis | 1.9 (1.29–2.82) | P = 0.001 | |
| Previous CPRExploratory multivariable analysis | 8.7 (1.09–69.2) | P = 0.041 | |
| MalignancyExploratory multivariable analysis | 2.4 (1.24–4.62) | P = 0.009 | |
| Age 2 to 5 yearsExploratory multivariable analysis | 4 (1.18–13.5) | P = 0.026 | |
| Age 6 to 8 yearsExploratory multivariable analysis | 4.86 (1.36–17.3) | P = 0.015 | |
| Age 9 to 11 yearsExploratory multivariable analysis | 6.46 (1.68–24.7) | P = 0.007 | |
| Age ≥ 12 yearsExploratory multivariable analysis | 7.49 (1.92–29.3) | P = 0.004 | |
| 0.050.21520Adjusted odds ratio (log scale) |
| Outcome | aOR (95% CI) | P value | |
|---|---|---|---|
| Postoperative ventilationIOH vs No IOH | 2.25 (1.07–4.73) | P < 0.001 | |
| 0.20.5125Adjusted odds ratio (log scale) |
Only one 5-minute epoch below threshold, among patients with IOH
- 309/529
- 58.4%
Original publication
Intraoperative Hypotension in Children Undergoing Noncardiac Surgery: An Exploratory Single-Center Analysis of Incidence, Associated Risk Factors, and Outcomes. Anesth Analg. Published 14 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →