Perioperative medicine & outcomes
Intraoperative QTc interval interpretation: Effects of anaesthesia, ECG, correction formulae, sex, and current limits: A Prospective Observational Study
Main finding · QT interval duration, 12-lead vs 5-lead ECGResult — go to the resultDifference - 0.09 msAuthors' conclusion
Intraoperative QTc interval measurement using a 5-lead ECG is valid. Correction formulae and gender influence the intraoperative QTc interval duration and the incidence of pathologically prolonged values according to current limits.
Study context
- Population
- Patients under GA with intraoperative QT/QTc monitoring44% males
- Participants
- 100 participants
- Exposure
- 5-lead ECG vs 12-lead ECG
- Outcome
- Agreement of automated continuous intraoperative QTc monitoring with 5-lead ECG vs 12-lead ECG
Main finding
QT interval duration, 12-lead vs 5-lead ECG
Difference
- 0.09 ms
P = 0.793
As reported in the abstract
Observational data: associations, not effects.
Further findings
Mean QTc duration, intraoperative vs resting ECGs of regional community-based population
QTc duration by correction formula (Bazett, Fridericia, Hodges, Framingham, Charbit, QTcRAS)
- QTc duration significantly differed between correction formulae
- P < 0.001
QTc duration by sex
- QTc duration significantly differed between sexes
- P < 0.001
Incidence of prolonged QTc >500 ms
- Significantly depended on correction formula
- P < 0.001
- Up to tenfold higher in women vs men
Original publication
Intraoperative QTc interval interpretation: Effects of anaesthesia, ECG, correction formulae, sex, and current limits: A Prospective Observational Study. Acta Anaesthesiol Scand. Published 26 September 2024. doi:10.
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