Pediatric anesthesia & critical care
Intraoperative transfusion practice and associated outcomes following neonatal surgery in a middle‐income country: A 5‐year single center retrospective review
Authors' conclusion
Intraoperative blood product transfusion occurred at a much higher rate with a high median pre-transfusion hemoglobin compared to other studies.
Study context
- Population
- Neonates undergoing surgery at Chris Hani Baragwanath Academic Hospital, January 1, 2015 to December 31, 2019
- Participants
- 1,078 anesthetic records
- Outcome
- Use of intraoperative blood product transfusion during neonatal surgery
Methodological detailssingle-centre, retrospective review of anesthetic records
- Single-centre
- Retrospective review of anesthetic records
Main finding
As reported in the abstract
Intraoperative blood product transfusion
- Any blood product transfused (surgeries)
- 374 (34.7%)
- Packed RBC transfused (surgeries)
- 327 (30.3%)
- Platelet concentrate transfused (surgeries)
- 133 (12.3%)
- FFP transfused (surgeries)
- 85 (7.9%)
- Packed RBC volume, median (IQR)
- 15 (10-21.8) mL/kg
- FFP volume, median (IQR)
- 12.3 (10-23.5) mL/kg
- Platelet volume, median (IQR)
- 13.6 (10-20.5) mL/kg
- Clear fluid volume, median (IQR)
- 19 (9.1-28.8) mL/kg
- Median preoperative hemoglobin
- 11.8 g/dL
Observational data: associations, not effects.
Further findings
Factors associated with blood product transfusion
- Very low weight, low preoperative hemoglobin, long total anesthetic time, emergency surgery and major surgery independently associated with transfusion
Factors associated with composite adverse outcomes
- Gestational age at birth, blood product transfusion, emergency surgery and major surgery independently associated with composite adverse outcomes
Original publication
Intraoperative transfusion practice and associated outcomes following neonatal surgery in a middle‐income country: A 5‐year single center retrospective review. Paediatr Anaesth. Published 27 June 2023. doi:10.
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