Pediatric anesthesia & critical care
Global neonatal perioperative mortality: A systematic review and meta-analysis
Authors' conclusion
The review demonstrated very high global POMRs in a surgical population of neonates independent of the country HDI level.
Study context
- Population
- Neonates undergoing procedures under anesthesia, studies published 2011–2022
- Participants
- 33,729 neonates · 18 studies · 45 countries
- Comparison
- Neonatal perioperative mortality rate (POMR) by country Human Development Index (HDI) level
- Outcome
- 24-h POMR
- Follow-up
- 24 h
Methodological detailsDatabases searched January 2011 to July 30, 2022
- Databases searched January 2011 to July 30, 2022
Pooled result
As reported in the abstract
Odds ratio (95% CI)P value
Low-HDI vs Very-high-HDI
8.4(1.7–40.4)
P = 0.008Low-HDI vs High-HDI
7.3(2.2–24.4)
P = 0.001Low-HDI vs Medium-HDI
7.7(3.1–18.7)
P < 0.0001- 24-h deaths
- 96
Further pooled results
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| 30-day POMR · 30 daysLow-HDI vs Very-high-HDI | 6.9 (1.9–24.6) | P = 0.002 | |
| 30-day POMR · 30 daysLow-HDI vs High-HDI | 1.4 (0.6–3.0) | P = 0.396 | |
| 0.050.21520Odds ratio (log scale) |
- 30-day POMR — 30-day deaths
- 459
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Global neonatal perioperative mortality: A systematic review and meta-analysis. J Clin Anesth. Published 6 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →