Pediatric anesthesia & critical care
Perioperative anaesthetic management and short-term outcome of neonatal repair of oesophageal atresia with or without tracheo-oesophageal fistula in Europe: A sub-analysis of the neonate and children audit of anaesthesia practice in Europe (NECTARINE) prospective multicenter observational study
Authors' conclusion
Oesophageal atresia with or without a tracheo-oesophageal fistula repair in neonates is associated with a high number of perioperative interventions in response to clinical events, a high incidence of postoperative complications, and a substantial mortality rate.
Study context
- Population
- Neonates undergoing first surgery for oesophageal atresia with or without tracheo-oesophageal fistula, European NECTARINE cohort
- Participants
- 103 neonates
- Primary endpoint
- Incidence of perioperative clinical events requiring a predetermined intervention, postoperative complications, and mortality
Methodological detailsmulticentre
- Multicentre
Primary result
As reported in the abstract
Perioperative clinical events
69%
95% CI 59 to 77%
30-day postoperative complications
47%
95% CI 38 to 57%
30-day mortality
2.1%
90-day mortality
2.6%
Further findings
Patient characteristics and monitoring
- Median gestational age (weeks)
- 38
- Median birth weight, grams (IQR 2150 to 3150)
- 2840
- Invasive monitoring used
- 66%
Original publication
Perioperative anaesthetic management and short-term outcome of neonatal repair of oesophageal atresia with or without tracheo-oesophageal fistula in Europe: A sub-analysis of the neonate and children audit of anaesthesia practice in Europe (NECTARINE) prospective multicenter observational study. Eur J Anaesthesiol. Published 28 September 2023. doi:10. 1097/ eja. 0000000000001905
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