Pediatric anesthesia & critical care

Perioperative anaesthetic management and short-term outcome of neonatal repair of oesophageal atresia with or without tracheo-oesophageal fistula in Europe: A sub-analysis of the neonate and children audit of anaesthesia practice in Europe (NECTARINE) prospective multicenter observational study

Eur J AnaesthesiolPublished Secondary analysis of the NECTARINE prospective observational study

Authors' conclusion

Oesophageal atresia with or without a tracheo-oesophageal fistula repair in neonates is associated with a high number of perioperative interventions in response to clinical events, a high incidence of postoperative complications, and a substantial mortality rate.

Study context

Population
Neonates undergoing first surgery for oesophageal atresia with or without tracheo-oesophageal fistula, European NECTARINE cohort
Participants
103 neonates
Primary endpoint
Incidence of perioperative clinical events requiring a predetermined intervention, postoperative complications, and mortality
Methodological detailsmulticentre
  • Multicentre

Primary result

As reported in the abstract

Perioperative clinical events

69%

95% CI 59 to 77%

30-day postoperative complications

47%

95% CI 38 to 57%

30-day mortality

2.1%

90-day mortality

2.6%

Further findings

Patient characteristics and monitoring

Median gestational age (weeks)
38
Median birth weight, grams (IQR 2150 to 3150)
2840
Invasive monitoring used
66%

Original publication

Perioperative anaesthetic management and short-term outcome of neonatal repair of oesophageal atresia with or without tracheo-oesophageal fistula in Europe: A sub-analysis of the neonate and children audit of anaesthesia practice in Europe (NECTARINE) prospective multicenter observational study. Eur J Anaesthesiol. Published 28 September 2023. doi:10.1097/eja.0000000000001905

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