Perioperative medicine & outcomes

Intraoperative Use of Vasoactive Agents in Non‐Cardiac Surgery: Protocol for a Post Hoc Cohort Study

Acta Anaesthesiol ScandPublished Protocol for a post hoc secondary analysis of the SQUEEZE international observational cohort study

Study context

Population
Adults undergoing non-cardiac, non-obstetric, non-transplant surgery as in-patients; data collected during one consecutive week per site, October 2020–October 2023≈19,000 planned
Primary endpoint
Proportion of patients who received intraoperative vasoactive treatment
Methodological detailsdescriptive, logistic regression, Secondary outcomes: proportion receiving each pre-specified agent; pre-specified postoperative complications incl. death and hospital LOS, Logistic regression of baseline variables vs intraoperative vasoactive therapy
  • Descriptive
  • Logistic regression
  • Secondary outcomes: proportion receiving each pre-specified agent; pre-specified postoperative complications incl. death and hospital LOS
  • Logistic regression of baseline variables vs intraoperative vasoactive therapy

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Intraoperative Use of Vasoactive Agents in Non‐Cardiac Surgery: Protocol for a Post Hoc Cohort Study. Acta Anaesthesiol Scand. Published 14 January 2026. doi:10.1111/aas.70188

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