Vasoactive-Inotropic Score in Orthotopic Liver Transplantation: A Retrospective Observational Study
Authors' conclusion
VIS calculated in the first 24 hours after OLTx showed a significant correlation with AKI in the first 7 postoperative days. VIS, calculated either intraoperatively or postoperatively, correlated with 30-day and 1-year mortality, duration of mechanical ventilation, and ICU length of stay.
Study context
- Population
- Patients undergoing orthotopic liver transplantation (OLTx), Jan 2018–Nov 2023, tertiary referral university hospital transplant centre
- Participants
- 144 patients
- Exposure
- Intraoperative and postoperative Vasoactive-Inotropic Score (VIS) and outcomes after OLTx
- Outcome
- Association between VIS and AKI
- Follow-up
- First 7 postoperative days
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
AKI in the first 7 postoperative days
Odds ratio
1.06
P = 0.03
postoperative VIS · postoperative VIS correlated with the incidence of acute kidney injury (AKI)
Odds ratio
3.63
P = 0.006
VIS > 10 vs VIS < 5
Observational data: associations, not effects.
Secondary outcomes
30-day mortality
| OR | P value | |
|---|---|---|
| Intraoperative VIS | 1.06 | P = 0.001 |
| Postoperative VIS | 1.11 | P < 0.001 |
1-year mortality
| OR | P value | |
|---|---|---|
| Intraoperative VIS | 1.04 | P < 0.001 |
| Postoperative VIS | 1.08 | P < 0.001 |
Length of mechanical ventilation
| R | P value | |
|---|---|---|
| Intraoperative VIS | 0.27 | P = 0.001 |
| Postoperative VIS | 0.36 | P < 0.001 |
Intensive care unit (ICU) LOS
| R | P value | |
|---|---|---|
| Intraoperative VIS | 0.18 | P = 0.03 |
| Postoperative VIS | 0.21 | P = 0.01 |
Original publication
Vasoactive-Inotropic Score in Orthotopic Liver Transplantation: A Retrospective Observational Study. J Cardiothorac Vasc Anesth. Published 10 April 2026. doi:10.
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