Intravenous vitamin C therapy in adult patients with sepsis: A rapid practice guideline
Methodological detailsGRADE approach, evidence-to-decision framework, based on updated systematic review
- GRADE approach
- Evidence-to-decision framework
- Based on updated systematic review
Recommendations
As issued by the authors
- conditional recommendation
Against using IV vitamin C therapy in sepsis, beyond standard nutritional supplementation (undesirable consequences judged to probably outweigh desirable; 90-day mortality RR 1.05, 95% CI 0.94 to 1.17, 6 trials, n = 2148, moderate certainty)
Original publication
Intravenous vitamin C therapy in adult patients with sepsis: A rapid practice guideline. Acta Anaesthesiol Scand. Published 27 July 2023. doi:10.
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