Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM

Bassetti, M; Giacobbe, DR; Agvald-Ohman, C; Akova, M; Alastruey-Izquierdo, A; Arikan-Akdagli, S; Azoulay, E; Blot, S; Cornely, OA; Cuenca-Estrella, M; de Lange, DW; De Rosa, FG; De Waele, JJ; Dimopoulos, G; Garnacho-Montero, J; Hoenigl, M; Kanj, SS; Koehler, P; Kullberg, BJ; Lamoth, F; Lass-Flörl, C; Maertens, J; Martin-Loeches, I; Muñoz, P; Poulakou, G; Rello, J; Sanguinetti, M; Taccone, FS; Timsit, JF; Torres, A; Vazquez, JA; Wauters, J; Asperges, E; Cortegiani, A; Grecchi, C; Karaiskos, I; Le Bihan, C; Mercier, T; Mortensen, KL; Peghin, M; Rebuffi, C; Tejada, S; Vena, A; Zuccaro, V; Scudeller, L; Calandra, T; Study Group for Infections in Critically Ill Patients of the European Society of Clinical Microbiology and Infectious Diseases (ESGCIP), the Fungal Infection Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EFISG), the European Society of Intensive Care Medicine (ESICM), the European Confederation of Medical Mycology (ECMM), the Mycoses Study Group Education and Research Consortium (MSGERC), the International Society of Antimicrobial Chemotherapy (ISAC), the International Society for Human and Animal Mycology (ISHAM), the Austrian Society for Medical Mycology (ÖGMM), the Italian Society of Anesthesia, Analgesia, Reanimation, and Intensive Care (SIAARTI), the Italian Society of Anti-Infective Therapy (SITA), and the FUNDICU Collaborators

doi:10.1007/s00134-024-07341-7

Sepsis & infection

Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM

Intensive Care MedPublished 21 Mar 2024Consensus statement

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Cite

Methodological detailsRAND/UCLA appropriateness method, systematic assessment of existing definitions and laboratory tests

RAND/UCLA appropriateness method
Systematic assessment of existing definitions and laboratory tests

Recommendations

As issued by the authors

Standardized research definitions for proven invasive candidiasis, probable deep-seated candidiasis, proven invasive aspergillosis, probable invasive pulmonary aspergillosis, and probable tracheobronchial aspergillosis
No dedicated definitions for invasive fungal diseases (IFD) other than candidiasis and aspergillosis, owing to limited evidence on performance of existing definitions and laboratory tests, at least pending further data

Reference

Issued by: ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM
Document: Consensus definitions
Scope: Standardized research definitions of invasive fungal diseases (IFD) in non-neutropenic adult ICU patients without classical host factors for IFD

Authors: Bassetti M, Giacobbe DR, Agvald-Ohman C, Akova M, Alastruey-Izquierdo A, Arikan-Akdagli S, et al.
All 47 authors
Bassetti M, Giacobbe DR, Agvald-Ohman C, Akova M, Alastruey-Izquierdo A, Arikan-Akdagli S, Azoulay E, Blot S, Cornely OA, Cuenca-Estrella M, de Lange DW, De Rosa FG, De Waele JJ, Dimopoulos G, Garnacho-Montero J, Hoenigl M, Kanj SS, Koehler P, Kullberg BJ, Lamoth F, Lass-Flörl C, Maertens J, Martin-Loeches I, Muñoz P, Poulakou G, Rello J, Sanguinetti M, Taccone FS, Timsit JF, Torres A, Vazquez JA, Wauters J, Asperges E, Cortegiani A, Grecchi C, Karaiskos I, Le Bihan C, Mercier T, Mortensen KL, Peghin M, Rebuffi C, Tejada S, Vena A, Zuccaro V, Scudeller L, Calandra T, Study Group for Infections in Critically Ill Patients of the European Society of Clinical Microbiology and Infectious Diseases (ESGCIP), the Fungal Infection Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EFISG), the European Society of Intensive Care Medicine (ESICM), the European Confederation of Medical Mycology (ECMM), the Mycoses Study Group Education and Research Consortium (MSGERC), the International Society of Antimicrobial Chemotherapy (ISAC), the International Society for Human and Animal Mycology (ISHAM), the Austrian Society for Medical Mycology (ÖGMM), the Italian Society of Anesthesia, Analgesia, Reanimation, and Intensive Care (SIAARTI), the Italian Society of Anti-Infective Therapy (SITA), and the FUNDICU Collaborators
Journal: Intensive Care Medicine
Published: 21 Mar 2024
DOI: 10.1007/s00134-024-07341-7
PubMed: 38512399

Topic: Sepsis & infection

Original publication

Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM. Intensive Care Med. Published 21 March 2024. doi:10.1007/s00134-024-07341-7

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