Respiratory failure & ventilation
Investigating the effects of pressure support ventilation and positive end-expiratory pressure during extubation on respiratory system complications
Authors' conclusion
The use of PSV and PEEP modes during extubation-emergence period in laparoscopic cholecystectomy results in a low rate of respiratory system complications, which are mostly minor.
Study context
- Population
- Patients extubated after laparoscopic cholecystectomy with pressure support ventilation (PSV) and positive end-expiratory pressure (PEEP) modes and remifentanil infusion199 evaluated
- Participants
- 37 vs 167
- Exposure
- Group I vs group 0
- Group In = 37
- Group 0n = 167reference
- Outcome
- Post-extubation respiratory complications
Main finding
As reported in the abstract
- Cough (3 or more, persistent or repetitive coughing)
- 12 patients (6.04%)
- Desaturation (SpO2 < 90% for 10 s)
- 9 patients (4.53%)
- Bronchospasm
- 8 patients (4.02%)
- Agitation (5 and above on the agitation scale)
- 3 patients (1.5%)
- Need for rescue mask ventilation (SpO2 < 90% lasting longer than 10 s)
- 3 patients (1.5%)
- Airway obstruction (2 and above according to laryngospasm score)
- 2 patients (1%)
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| ASA III, group I vs group 0Statistically significant difference | P = 0.0365 |
Original publication
Investigating the effects of pressure support ventilation and positive end-expiratory pressure during extubation on respiratory system complications. Perioper Med (Lond). Published 18 December 2024. doi:10.
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