Hemodynamics, fluids & transfusion

Issuing of isotonic crystalloid solutions to Danish public hospitals in 2021—A retrospective nationwide observational study

Acta Anaesthesiol ScandPublished Retrospective nationwide observational study

Authors' conclusion

In this nationwide observational study, we found that the issuing of different isotonic crystalloid solutions varied based on geographical location.

Study context

Population
Danish public hospitals, isotonic crystalloid solutions (0.9% saline, acetate- and lactate-buffered) issued 1 January–31 December 2021
Exposure
Medical vs Emergency vs Surgical vs Anaesthesiological
Outcome
Issuing of isotonic crystalloid solutions at national, regional, hospital and departmental level
Follow-up
2021
Methodological detailsdescriptive, Sales figures from the Danish Regional Hospital Pharmacies
  • Descriptive
  • Sales figures from the Danish Regional Hospital Pharmacies

Main finding

As reported in the abstract

Isotonic crystalloid solutions issued nationally
Total issued
1,487,144 L
Saline
67.4%
Acetate-buffered
25.9%
Lactate-buffered
6.7%
Per hospitalised patient
2.1 L

Observational data: associations, not effects.

Further findings

Proportion of saline by department · 2021

Original publication

Issuing of isotonic crystalloid solutions to Danish public hospitals in 2021—A retrospective nationwide observational study. Acta Anaesthesiol Scand. Published 27 December 2022. doi:10.1111/aas.14176

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