Hemodynamics, fluids & transfusion

Issuing of albumin solutions to Danish public hospitals—A nationwide, retrospective, observational study based on pharmacy data from 2022

Acta Anaesthesiol ScandPublished Retrospective observational study

Authors' conclusion

In this nationwide study on the issuing of albumin, we observed differences across regional, hospital, and departmental settings.

Study context

Population
All Danish public hospitals, 2022
Exposure
Albumin issuing relative to total fluids across regions, hospital types and departments
Outcome
Issuing of IV albumin solutions (5% and 20%) relative to total issued fluids (colloid and isotonic crystalloid solutions)
Follow-up
2022
Methodological detailsnationwide, pharmacy purchasing data, descriptive, Purchasing data from Danish regional hospital pharmacies used as estimate of fluid issuing
  • Nationwide
  • Pharmacy purchasing data
  • Descriptive
  • Purchasing data from Danish regional hospital pharmacies used as estimate of fluid issuing

Main finding

As reported in the abstract

Albumin share of total fluid issued
Total fluid issued
1,543,199 L
Albumin solutions issued
14,888 L (1%)
Range across geographical regions
0.4% to 1.6%

Observational data: associations, not effects.

Further findings

Albumin share of fluid issued by department

Intensive care units (ICUs)
2.9%
Anaesthesia departments
2.2%
Medical departments
0.8%
Surgical departments
0.3%
EDs
0.1%

Geographical variation in albumin share within department types

ICUs
1.1% to 5.2%
Anaesthesia departments
0.2% to 5.6%

Original publication

Issuing of albumin solutions to Danish public hospitals—A nationwide, retrospective, observational study based on pharmacy data from 2022. Acta Anaesthesiol Scand. Published 3 January 2025. doi:10.1111/aas.14570

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