Perioperative medicine & outcomes
Just What the Doctor Ordered: Missed Ordering of Venous Thromboembolism Chemoprophylaxis Is Associated With Increased Venous Thromboembolism (VTE) Events in High-risk General Surgery Patients
Main findingResult — go to the resultOdds ratio 0.50 95% CI 0.30–0.80Authors' conclusion
pVTE ordering in high-risk general surgery patients was associated with 42% reduction in odds of postoperative 30-day VTE.
Study context
- Population
- Adult high-risk (2010 Caprini score ≥5) general surgery inpatients without bleeding history and/or acute renal failure, Atrium Health NSQIP registry, 2016–2019high-risk inpatients of 19,578
- Participants
- 4,252 participants
- Exposure
- Perfect VTE chemoprophylaxis orders vs not
- Outcome
- Postoperative VTE
- Follow-up
- 30 days
Methodological detailsregistry-based, multivariable analysis
- Registry-based
- Multivariable analysis
Main finding
As reported in the abstract
Odds ratio
0.50
95% CI 0.30–0.80
pVTE vs No pVTE
OR 0.50 (95% CI 0.30–0.80)
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| VTE event/mortality | 0.45 (0.31–0.63) | |
| 0.20.5125Odds ratio (log scale) |
Hospital compliance with pVTE
- pVTE compliance
- 32.4%
Postoperative LOS and perioperative RBC transfusions
- pVTE associated with shorter postoperative LOS and fewer perioperative RBC transfusions
Original publication
Just What the Doctor Ordered: Missed Ordering of Venous Thromboembolism Chemoprophylaxis Is Associated With Increased VTE Events in High-risk General Surgery Patients. Ann Surg. Published 15 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →