Cardiothoracic & vascular anesthesia
Landiolol for the prevention of postoperative atrial fibrillation after cardiac surgery: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials
Pooled result · Incidence of POAFResult — go to the resultOdds ratio 0.35 95% CI 0.23–0.53Authors' conclusion
Landiolol appears to be an effective agent for the prevention of POAF in patients undergoing cardiac surgeries.
Study context
- Population
- Patients undergoing cardiac surgery
- Participants
- 1,264 patients · 11 randomized clinical trials (RCTs)
- Comparison
- Landiolol vs control
- Outcome
- Incidence of postoperative AF (postoperative atrial fibrillation (POAF))
Methodological detailsGRADE-assessed
- GRADE-assessed
Pooled result
Incidence of POAF
Odds ratio
0.35
95% CI 0.23–0.53
P < 0.01
Landiolol vs Control
OR 0.35 (95% CI 0.23–0.53); P < 0.01
As reported in the abstract
Further pooled results
Hospital mortality, hospital LOS, HF, major complications
- No significant differences between landiolol and control
Original publication
Landiolol for the prevention of postoperative atrial fibrillation after cardiac surgery: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials. Anaesth Crit Care Pain Med. Published 30 March 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →