Cardiac arrest & resuscitation
Layperson-Administered Naloxone Trends Reported in Emergency Medical Service Activations, 2020-2022
Authors' conclusion
In this cross-sectional study, the LAN rate increased from June 2020 to June 2022 as reported in the national EMS database.
Study context
- Population
- Persons receiving naloxone during US emergency medical services (EMS) activations (911 responses, standbys, intercept or mutual aid), June 2020 to June 2022; health care settings and interfacility or medical transports excluded
- Participants
- 65,621,195 EMS activations
- Outcome
- Trend of receiving layperson-administered naloxone (LAN), by EMS clinician documentation
Methodological detailsnational registry (National Emergency Medical Services Information System (NEMSIS)), Data from the National Emergency Medical Services Information System (NEMSIS)
- National registry (NEMSIS)
- Data from the National Emergency Medical Services Information System (NEMSIS)
Main finding
As reported in the abstract
LAN rate per 100 000 EMS activations · June 2020 to June 2022
Layperson-administered naloxone (LAN) rate, start
30.0
per 100 000 EMS activations; 95% CI 29.2–30.8
LAN rate, end
43.1
per 100 000 EMS activations; 95% CI 42.0–44.1
Percentage change in LAN
increased 43.5%
Patients receiving naloxone with LAN
24 990
3.4%
Observational data: associations, not effects.
Further findings
Overall naloxone administration rate per 100 000 EMS activations · June 2020 to June 2022
- Rate, start
- 1140.1 (95% CI 1135.1-1145.1)
- Rate, end
- 1070.1 (95% CI 1064.9-1075.3)
- Percentage change
- decreased 6.1%
Naloxone recipients
- Patients receiving naloxone
- 744 078
- Suspected drug overdose as primary or secondary impression
- 243 985 (32.8%)
Characteristics of LAN recipients
- Male
- 17 331 [69.4%]
- Median (IQR) age, years
- 42 (31-56)
- Urban
- 21 692 [86.8%]
- In-home or residence
- 13 223 [52.9%]
Original publication
Layperson-Administered Naloxone Trends Reported in Emergency Medical Service Activations, 2020-2022. JAMA Netw Open. Published 1 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →