ICU sedation, delirium & recovery
Long-stay intensive care unit (ICU) patients with frailty: mortality and recovery outcomes at 6 months
Authors' conclusion
Frailty is associated with increased mortality and poorer physical health-related QoL in long-stay ICU patients at 6 months.
Study context
- Population
- Patients hospitalized ≥ 7 days in the ICU, May 2018–May 2021
- Participants
- 531 patients
- Exposure
- Frail vs pre-frail vs non-frail at ICU admission
- Frailn = 178
- Pre-frailn = 200
- Non-frailn = 153reference
- Outcome
- Mortality
- Follow-up
- Up to 6 months
Main finding
As reported in the abstract
Each group vs non-frailAdjusted hazard ratio (95% CI)
Pre-frail
1.7(0.9–2.9)
Frail
2.9(1.7–4.9)
Observational data: associations, not effects.
Further findings
Withdrawing or withholding of care
- Did not differ significantly between the groups
Health-related quality of life (QoL) · up to 6 months
- Clinical Frailty Scale (CFS) ≥ 5 vs CFS 1-2 associated with poorer physical health-related QoL, not poorer mental health-related QoL
- 192 seen at follow-up consultation
- Multivariate linear regressions
Original publication
Long-stay ICU patients with frailty: mortality and recovery outcomes at 6 months. Ann Intensive Care. Published 24 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →