Cardiac arrest & resuscitation
Long-term heart function in refractory out-of-hospital cardiac arrest treated with prehospital extracorporeal cardiopulmonary resuscitation
Authors' conclusion
Most patients who were treated with prehospital ECPR for refractory OHCA due to ACS and survived with good neurological outcomes recovered a good heart function at one year, and half of them were working.
Study context
- Population
- Refractory out-of-hospital cardiac arrest (OHCA) caused by acute coronary syndrome (ACS) treated with prehospital extracorporeal cardiopulmonary resuscitation (ECPR), Paris, France, 2015–2023
- Participants
- 114 participants
- Outcome
- NYHA functional class
- Follow-up
- One year
Methodological detailsmonocentric, Paris, France, January 1, 2015, to December 31, 2023
- Monocentric
- Paris, France, January 1, 2015, to December 31, 2023
Main finding
As reported in the abstract
New York Heart Association Functional Classification (NYHA-FC) among 1-year survivors with good neurological outcome (n=24)
Prehospital ECPR
1
median · IQR 1–1
Observational data: associations, not effects.
Further findings
Survival with good neurological outcome (CPC 1 or 2) · 1 year
- Survived with good neurological outcome (CPC 1 or 2)
- 24/114 (21 %)
Left ventricular ejection fraction (LVEF) recovery (>50 %) among survivors with good neurological outcome · 1 year
- Half recovered LVEF > 50 %
Ability to work among patients still alive · median follow-up 6.8 (3.6-8.0) years
- Patients still alive
- 21
- Median time to regain ability to work since OHCA onset
- 10 months (3-21)
- Half actively working
Original publication
Long-term heart function in refractory out-of-hospital cardiac arrest treated with prehospital extracorporeal cardiopulmonary resuscitation. Resuscitation. Published 30 November 2024. doi:10.
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