Organ support & nutrition

Long-Term Outcomes After Acute Kidney Injury During Hospitalization: A Systematic Review and Meta-Analysis of Matched Controls Studies

Crit Care MedPublished Systematic review and meta-analysis of matched controls studies

Pooled result · Long-term mortalityResult — go to the resultRelative risk 1.42 95% CI 1.13–1.78

Authors' conclusion

Compared with controls, patients who experienced an episode of AKI and survived to hospital discharge have an increased risk of death, dialysis, and CKD.

Study context

Population
Hospital survivors with vs without acute kidney injury (AKI), minimum follow-up 1 year
Participants
1,058,109 survivors · 14 studies
Comparison
AKI vs no AKI during hospitalisation
Outcome
Long-term mortality
Follow-up
Longest available for each study
Methodological detailsTwo independent investigators extracted data; discrepancies resolved by consensus
  • Two independent investigators extracted data; discrepancies resolved by consensus

Pooled result

As reported in the abstract

Relative risk

1.42

95% CI 1.13–1.78

P = 0.002

Events by group

AKI vs Controls
RR 1.42 (95% CI 1.13–1.78); P = 0.002

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Long-Term Outcomes After Acute Kidney Injury During Hospitalization: A Systematic Review and Meta-Analysis of Matched Controls Studies. Crit Care Med. Published 17 November 2025. doi:10.1097/ccm.0000000000006953

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