Cardiothoracic & vascular anesthesia

Renal pulsatility index assessment by intraoperative doppler ultrasound is associated with acute kidney injury after cardiac surgery: a prospective observational study

J Clin AnesthPublished Prospective observational study

Main finding · AKI incidence and association with RPI at T3 (immediately after surgery)Result — go to the resultOdds ratio 3.72 95% CI 1.92–7.20

Authors' conclusion

An elevated RPI immediately after surgery was associated with increased risk of AKI after cardiac surgery.

Study context

Population
Patients undergoing cardiac surgery
Participants
500 patients
Exposure
Acute kidney injury (AKI) vs No AKI
  • AKIn = 161
Outcome
Incidence of AKI (KDIGO-defined)
Methodological detailsmultivariable logistic regression, restricted cubic splines
  • Multivariable logistic regression
  • Restricted cubic splines

Main finding

As reported in the abstract

AKI incidence and association with RPI at T3 (immediately after surgery)

Odds ratio

3.72

95% CI 1.92–7.20

P < 0.001

Intraoperative renal pulsatility index (RPI) by Doppler ultrasound vs postoperative AKI
OR 3.72 (95% CI 1.92–7.20); P < 0.001
Patients developing AKI
161 (32.2%)

Observational data: associations, not effects.

Further findings

OutcomeAKINo AKIP value
RPI at T3 (immediately after surgery)1.44 ± 0.341.30 ± 0.28P = 0.004

Renal pulsatility index (RPI) at T3 (immediately after surgery)

No significant differences in RPI at the other time points (T0–T2)

Moderate to severe AKI

Patients with moderate to severe AKI
46

RPI cutoff at T3 (restricted cubic splines)

RPI cutoff above which AKI risk increased proportionally
1.305

Original publication

Renal pulsatility index assessment by intraoperative doppler ultrasound is associated with acute kidney injury after cardiac surgery: a prospective observational study. J Clin Anesth. Published 28 April 2026. doi:10.1016/j.jclinane.2026.112217

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