Cardiothoracic & vascular anesthesia
Renal pulsatility index assessment by intraoperative doppler ultrasound is associated with acute kidney injury after cardiac surgery: a prospective observational study
Main finding · AKI incidence and association with RPI at T3 (immediately after surgery)Result — go to the resultOdds ratio 3.72 95% CI 1.92–7.20Authors' conclusion
An elevated RPI immediately after surgery was associated with increased risk of AKI after cardiac surgery.
Study context
- Population
- Patients undergoing cardiac surgery
- Participants
- 500 patients
- Exposure
- Acute kidney injury (AKI) vs No AKI
- AKIn = 161
- Outcome
- Incidence of AKI (KDIGO-defined)
Methodological detailsmultivariable logistic regression, restricted cubic splines
- Multivariable logistic regression
- Restricted cubic splines
Main finding
As reported in the abstract
AKI incidence and association with RPI at T3 (immediately after surgery)
Odds ratio
3.72
95% CI 1.92–7.20
P < 0.001
Intraoperative renal pulsatility index (RPI) by Doppler ultrasound vs postoperative AKI
OR 3.72 (95% CI 1.92–7.20); P < 0.001
- Patients developing AKI
- 161 (32.2%)
Observational data: associations, not effects.
Further findings
| Outcome | AKI | No AKI | P value |
|---|---|---|---|
| RPI at T3 (immediately after surgery) | 1.44 ± 0.34 | 1.30 ± 0.28 | P = 0.004 |
Renal pulsatility index (RPI) at T3 (immediately after surgery)
- No significant differences in RPI at the other time points (T0–T2)
Moderate to severe AKI
- Patients with moderate to severe AKI
- 46
RPI cutoff at T3 (restricted cubic splines)
- RPI cutoff above which AKI risk increased proportionally
- 1.305
Original publication
Renal pulsatility index assessment by intraoperative doppler ultrasound is associated with acute kidney injury after cardiac surgery: a prospective observational study. J Clin Anesth. Published 28 April 2026. doi:10. 1016/ j. jclinane. 2026. 112217
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