Pediatric anesthesia & critical care
Intraoperative renal and cerebral tissue oxygen saturation measurements to predict postoperative acute kidney injury in pediatric cardiac surgery: a prospective observational study
Authors' conclusion
A decrease in intraoperative renal or cerebral tissue oxygen saturation was not associated with postoperative AKI in pediatric patients undergoing surgery for non-cyanotic congenital heart disease.
Study context
- Population
- Pediatric patients with non-cyanotic heart disease undergoing elective surgical repair with CPB
- Participants
- 50 patients
- Exposure
- Acute kidney injury (AKI) vs No AKI
- Outcome
- Association between intraoperative SrO2 and ScO2 decreases (10% and 20% from baseline) and postoperative AKI (KDIGO criteria)
Main finding
As reported in the abstract
Intraoperative SrO2 and ScO2 reductions below 10% and 20% from baseline and postoperative AKI
P = 0.117
Observational data: associations, not effects.
Secondary outcomes
Incidence of postoperative AKI
- Incidence of postoperative AKI
- 18.4%
Other risk factors for AKI
- Preoperative serum creatinine, BMI, intraoperative hypotension and blood lactate associated with postoperative AKI
Original publication
Intraoperative renal and cerebral tissue oxygen saturation measurements to predict postoperative acute kidney injury in pediatric cardiac surgery: a prospective observational study. J Clin Monit Comput. Published 3 September 2025. doi:10.
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