Pediatric anesthesia & critical care
First Characterization of Tissue Oxygen Saturation Recovery Patterns in Pediatric Cardiac Surgery Patients Undergoing Remote Ischemic Preconditioning and the Association With Clinical Outcomes
Authors' conclusion
Specific patterns of SrO2 response to RIPC may serve as important indicators for risk stratification in congenital heart surgery.
Study context
- Population
- Children (<18 y) scheduled for elective cardiac surgery with CPB, Fundación Valle Del Lili, August 2022–July 2023
- Exposure
- Saturation (SrO2) response patterns during remote ischemic preconditioning (RIPC)
- Outcome
- SrO2 patterns during RIPC and postoperative outcomes
Methodological detailssingle-centre, RIPC after anaesthetic induction: cycles of ischaemia and reperfusion on a lower limb; SrO2 monitored by near-infrared spectroscopy (NIRS)
- Single-centre
- RIPC after anaesthetic induction: cycles of ischaemia and reperfusion on a lower limb; SrO2 monitored by NIRS
Main finding
As reported in the abstract
- 4 distinct SrO2 patterns identified during RIPC
- Negative SrO2 pattern significantly associated with more postoperative adverse events, incl. longer hospital LOS and higher mortality
- Positive pattern associated with better outcomes
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
First Characterization of Tissue Oxygen Saturation Recovery Patterns in Pediatric Cardiac Surgery Patients Undergoing Remote Ischemic Preconditioning and the Association With Clinical Outcomes. J Cardiothorac Vasc Anesth. Published 2 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →