ICU sedation, delirium & recovery

Long‐term outcomes in COVID‐19 patients admitted to intensive care in Denmark: A nationwide observational study

Acta Anaesthesiol ScandPublished Nationwide observational cohort study

Authors' conclusion

In Danish ICUs, the use of life support declined, while mortality seemed unchanged throughout the three waves of COVID-19.

Study context

Population
All Danish ICU patients with COVID-19, March 10, 2020 to March 31, 2022
Participants
2,167 patients
Exposure
Three COVID-19 waves; unvaccinated vs vaccinated ICU patients
  • First waven = 327reference
  • Second waven = 1,053
  • Third waven = 787
Outcome
90-day mortality
Follow-up
90 days
Methodological detailsmanual medical record review
  • Manual medical record review

Main finding

As reported in the abstract

  • 90-day mortality remained constant over the three waves

Observational data: associations, not effects.

Further findings

ICU LOS — Second wave
median 10 days

Vaccination rate, ICU patients vs society

Vaccination rate among ICU patients
42%
Vaccination rate in society
80%

Unvaccinated vs vaccinated: age, comorbidity, 90-day mortality

Age, unvaccinated vs vaccinated (median, years)
57 vs. 73
Comorbidity, unvaccinated vs vaccinated
50% vs. 78%
90-day mortality, unvaccinated vs vaccinated
29% vs. 51%

Use of COVID-specific pharmacological agents after Omicron became dominant

Decrease from 95% to 69%

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Long‐term outcomes in COVID‐19 patients admitted to intensive care in Denmark: A nationwide observational study. Acta Anaesthesiol Scand. Published 8 June 2023. doi:10.1111/aas.14290

Composed by AI from the published abstract and checked against it. How Briefs are made →

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