Sepsis & infection

Labour market attachment before and after hospitalisation for sepsis: a Danish cohort study

Crit CarePublished Register-based cohort study

Authors' conclusion

Most working-age patients with sepsis were outside the workforce. Working before sepsis was the strongest predictor of RTW. While educational level influenced whether patients were part of the workforce, it was not associated with RTW among those working. No ICU admission was associated with RTW.

Study context

Population
Patients aged 20–63 years with incident community-acquired sepsis admitted to hospital in the Region of Southern Denmark, 1 January 2016 to 20 March 2018
Participants
1,610 patients
Exposure
Workforce vs Working
  • Workforcen = 651
  • Workingn = 488
Outcome
RTW among the workforce and those working
Follow-up
12, 52, 104, and 156 weeks
Methodological detailsRegion of Southern Denmark, cause-specific hazards
  • Region of Southern Denmark
  • Cause-specific hazards

Main finding

As reported in the abstract

RTW, workforce (excluding those censored)

Return to work (RTW) after 12 weeks

69.0%

RTW after 52 weeks

81.6%

RTW after 104 weeks

87.5%

RTW after 156 weeks

90.4%

Observational data: associations, not effects.

Further findings

Factors associated with RTW among the workforce

HR (95% CI)
Younger age (20-39 years)1.33 (1.05–1.68)
No ICU admission2.64 (1.81–3.86)
Lactate < 4 mmol/L2.19 (1.13–4.24)
Single organ failure2.33 (1.16–4.69)

Intensive care unit (ICU) admission and educational level vs RTW

ICU admission had impact on RTW in both the workforce and those working; educational level unrelated to RTW among those working

Original publication

Labour market attachment before and after hospitalisation for sepsis: a Danish cohort study. Crit Care. Published 19 May 2025. doi:10.1186/s13054-025-05446-z

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