Return to work after hospitalization for sepsis: a nationwide, registry-based cohort study
Authors' conclusion
Absence of improvement in RTW proportions over time and the low probability of sustainable RTW in sepsis patients need attention
Study context
- Population
- Working-age patients (18–60 years) working before admission to a Norwegian hospital with sepsis, 2010–2021hospitalizations, of 35.839
- Participants
- 12.260 patients
- Exposure
- Intensive care unit (ICU) vs non-ICU and COVID-19 vs non-COVID-19 sepsis patients
- Outcome
- Proportion of RTW
- Follow-up
- 6 months, 1 year, and 2 years after discharge
Methodological detailsnationwide, registry-based, Mean age 43.7 years
- Nationwide
- Registry-based
- Mean age 43.7 years
Main finding
As reported in the abstract
Proportion working (RTW), overall
Working at 6 months post-discharge
58.6%
Working at 1 year post-discharge
67.5%
Working at 2 years post-discharge
63.4%
Observational data: associations, not effects.
Secondary outcomes
| Outcome | HR (95% CI) | |
|---|---|---|
| Sustainable RTW (31 days of consecutive work), ICU vs non-ICU (subgroup) | 0.56 (0.52–0.61) | |
| Sustainable RTW, COVID-19 vs non-COVID-19 sepsis (subgroup) | 1.31 (1.15–1.49) | |
| 0.512Hazard ratio (log scale) |
Time trends in age-standardized return to work (RTW) (ICU and non-ICU)
- 2-year age-standardized RTW, non-ICU: change per year
- 1.51% decline (95% CI - 2.22 to - 0.79)
- 2-year age-standardized RTW, non-ICU, 2010
- 70.01% (95% CI 67.21 to 74.80)
- 2-year age-standardized RTW, non-ICU, 2019
- 57.04% (95% CI 53.81-60.28)
- Stable over the study period, except 2-year RTW for non-ICU patients
Characteristics associated with sustainable RTW
- Younger age, fewer comorbidities and fewer acute organ dysfunctions
Original publication
Return to work after hospitalization for sepsis: a nationwide, registry-based cohort study. Crit Care. Published 15 November 2023. doi:10. 1186/ s13054-023-04737-7
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