Sepsis & infection

Return to work after hospitalization for sepsis: a nationwide, registry-based cohort study

Crit CarePublished Retrospective cohort study

Authors' conclusion

Absence of improvement in RTW proportions over time and the low probability of sustainable RTW in sepsis patients need attention

Study context

Population
Working-age patients (18–60 years) working before admission to a Norwegian hospital with sepsis, 2010–2021hospitalizations, of 35.839
Participants
12.260 patients
Exposure
Intensive care unit (ICU) vs non-ICU and COVID-19 vs non-COVID-19 sepsis patients
Outcome
Proportion of RTW
Follow-up
6 months, 1 year, and 2 years after discharge
Methodological detailsnationwide, registry-based, Mean age 43.7 years
  • Nationwide
  • Registry-based
  • Mean age 43.7 years

Main finding

As reported in the abstract

Proportion working (RTW), overall

Working at 6 months post-discharge

58.6%

Working at 1 year post-discharge

67.5%

Working at 2 years post-discharge

63.4%

Observational data: associations, not effects.

Secondary outcomes

OutcomeHR (95% CI)
Sustainable RTW (31 days of consecutive work), ICU vs non-ICU (subgroup)0.56 (0.52–0.61)
Sustainable RTW, COVID-19 vs non-COVID-19 sepsis (subgroup)1.31 (1.15–1.49)

Time trends in age-standardized return to work (RTW) (ICU and non-ICU)

2-year age-standardized RTW, non-ICU: change per year
1.51% decline (95% CI - 2.22 to - 0.79)
2-year age-standardized RTW, non-ICU, 2010
70.01% (95% CI 67.21 to 74.80)
2-year age-standardized RTW, non-ICU, 2019
57.04% (95% CI 53.81-60.28)
Stable over the study period, except 2-year RTW for non-ICU patients

Characteristics associated with sustainable RTW

Younger age, fewer comorbidities and fewer acute organ dysfunctions

Original publication

Return to work after hospitalization for sepsis: a nationwide, registry-based cohort study. Crit Care. Published 15 November 2023. doi:10.1186/s13054-023-04737-7

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