Long-term outcomes of patients supported with extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis
Authors' conclusion
Survivors of ECMO for ARDS experience significant disability in multiple domains.
Study context
- Population
- Patients supported with extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS)1 RCT and 31 observational studies
- Comparison
- ECMO vs conventional mechanical ventilation
- Outcome
- Health-related quality of life (HRQoL)
Methodological detailsStudy quality mostly low (45%) or fair (32%)
- Study quality mostly low (45%) or fair (32%)
Pooled result
As reported in the abstract
HRQoL (SF-36)
Mean difference
3.91
CI - 6.22 to 14.05
physical component score (PCS)
Mean difference
1.33
CI - 3.93 to 6.60
mental component score (MCS)
Further pooled results
Cognitive function, mental health, functional status, respiratory symptoms
- No difference between ECMO and conventional mechanical ventilation (CMV); comparison data limited
Return to work and assistance at home, ECMO survivors · follow-up
- Returned to work
- 49%
- Needed assistance at home
- 23%
- High rates of disability
Original publication
Long-term outcomes of patients supported with extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis. Intensive Care Med. Published 10 January 2024. doi:10.
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