Perioperative medicine & outcomes
Long-term Outcomes with Spinal versus General Anesthesia for Hip Fracture Surgery: A Randomized Trial
Primary result · DeathsResult — go to the resultHazard ratio 1.08 95% CI 0.81–1.44Authors' conclusion
Long-term outcomes were similar with spinal versus general anesthesia.
Study context
- Population
- Previously ambulatory patients ≥50 yr undergoing hip fracture repair at 46 US and Canadian hospitalsvital status available for 1,427 (89.2%)
- Participants
- 1,600 patients
- Comparison
- Spinal vs general anaesthesia for hip fracture repair
- Spinaln = 795
- Generaln = 805reference
- Primary endpoint
- Survival
- Follow-up
- Up to 365 days after randomization
Methodological detailssuperiority, multicentre, stratified randomisation, masked outcome assessment
- Superiority
- Multicentre
- Stratified randomisation
- Masked outcome assessment
Primary result
Deaths
Hazard ratio
1.08
95% CI 0.81–1.44
P = 0.59
Events by treatment group
Spinal
98
events
General
92
events
Spinal vs General
HR 1.08 (95% CI 0.81–1.44); P = 0.59
As reported in the abstract
Further findings
| Outcome | aOR for recovery of ambulation (95% CI) | P value | |
|---|---|---|---|
| Recovery of ambulation among 1-yr survivors · up to 365 daysDid not differ by type of anesthesia | 0.87 (0.67–1.14) | P = 0.31 | |
| 0.512AOR for recovery of ambulation (log scale) |
Other outcomes (composites of death or new inability to ambulate and death or new nursing home residence at 365 days)
- Did not differ by treatment arm
Original publication
Long-term Outcomes with Spinal versus General Anesthesia for Hip Fracture Surgery: A Randomized Trial. Anesthesiology. Published 13 October 2023. doi:10. 1097/ aln. 0000000000004807
Composed by AI from the published abstract and checked against it. How Briefs are made →