Cardiac arrest & resuscitation
Long-term survival following out-of-hospital cardiac arrest in women and men: Influence of comorbidities, social characteristics, and resuscitation characteristics
Authors' conclusion
Women survived longer than men post-OHCA. Several characteristics were associated with long-term post-OHCA survival, with some sex-specific characteristics. In both sexes, these characteristics had low predictive potential.
Study context
- Population
- Individuals aged ≥25 years who survived 30 days post-OHCA in 2009–2015 in Denmark and the Netherlands, followed until 20192,452 Danish
- Exposure
- Women vs men surviving 30 days post-OHCA
- Outcome
- Long-term survival (mortality IRR, women vs men)
- Follow-up
- Until 2019
Methodological detailsDanish and Dutch cohorts, age- and sex-matched general population comparison
- Danish and Dutch cohorts
- Age- and sex-matched general population comparison
Main finding
As reported in the abstract
Mortality
Women vs MenAdjusted incidence rate ratio (95% CI)
Denmark
0.74(0.61–0.89)
Netherlands
0.86(0.65–1.15)
Observational data: associations, not effects.
Further findings
| Outcome | IRR (95% CI) | |
|---|---|---|
| Mortality vs age- and sex-matched general population (Denmark)Women vs General population · Danish women | 3.07 (2.55–3.70) | |
| Mortality vs age- and sex-matched general population (Denmark)Men vs General population · Danish men | 2.15 (1.95–2.37) | |
| 0.20.5125Incidence rate ratio (log scale) |
Characteristics associated with shorter survival
- Both sexes: higher age, glucose lowering medication, no dyslipidaemia medication, unemployment, non-shockable initial rhythm
- Men: CV medication, depression/anxiety medication, living alone, low household income, residential out-of-hospital cardiac arrest (OHCA) location
- Women: not living with children, bystander CPR provision
Predictive value (Concordance-index)
- Concordance-indexes range
- 0.51 to 0.63
Original publication
Long-term survival following out-of-hospital cardiac arrest in women and men: Influence of comorbidities, social characteristics, and resuscitation characteristics. Resuscitation. Published 10 June 2024. doi:10.
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