Cardiac arrest & resuscitation
Sex-related disparities in post-cardiac arrest: a cohort study
Main finding · Favorable neurological outcome (mRS 0-3)Result — go to the resultOdds ratio 1.00 95% CI 0.73–1.37Authors' conclusion
Although women presented with worse unadjusted outcomes and more severe prognostic profiles, sex was not independently related to neurological recovery and mortality.
Study context
- Population
- Consecutive comatose adults admitted after CA to Lausanne University Hospital (CHUV), January 2016–February 2025, surviving the first 24 h28.6% women
- Participants
- 944 adults
- Exposure
- Women vs men
- Outcome
- Favorable outcome (modified Rankin Scale 0-3); ICU mortality and mortality
- Follow-up
- 3 months
Methodological detailsprospective registry, single-centre, consecutive patients, multivariable logistic regression
- Prospective registry
- Single-centre
- Consecutive patients
- Multivariable logistic regression
Main finding
Favorable neurological outcome (modified Rankin Scale (mRS) 0-3)
Odds ratio
1.00
95% CI 0.73–1.37
By group
Women vs Men
OR 1.00 (95% CI 0.73–1.37)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| ICU mortality (adjusted) | 1.08 (0.80–1.46) | |
| Mortality (adjusted) · 3 months | 1.05 (0.77–1.43) | |
| 0.512Odds ratio (log scale) |
CA characteristics and prognostic indicators
- Women more often non-cardiac etiology and non-shockable rhythm; more malignant EEG patterns, absent SSEP, higher serum NSE
Original publication
Sex-related disparities in post-cardiac arrest: a cohort study. Resuscitation. Published 16 April 2026. doi:10.
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