Cardiac arrest & resuscitation

Sex disparities in ICU care and outcomes after cardiac arrest: a Swiss nationwide analysis

Crit CarePublished Retrospective cohort study

Authors' conclusion

This study highlights sex disparities in short-term mortality and ICU resource allocation among cardiac arrest patients, with women potentially facing disadvantages, in particular after OHCA.

Study context

Population
Adult IHCA and out-of-hospital cardiac arrest (OHCA) patients, certified Swiss intensive care units (ICUs), 01/2008–12/202221,692 admitted to ICUs
Participants
41,733 participants
Exposure
Women vs men after cardiac arrest
Outcome
ICU mortality
Methodological detailsnationwide prospective ICU registry
  • Nationwide prospective ICU registry

Main finding

As reported in the abstract

P < 0.001

Observational data: associations, not effects.

Secondary outcomes

OutcomeIRR (95% CI)
ICU admission probabilityWomen less likely to be admitted to ICU0.82 (0.80–0.85)

Interventions before ICU stay

P < 0.001

Treatment limitations (subgroup, n = 11,202)

P < 0.001

ICU mortality, OHCA (subgroup)

Unadjusted HR, women vs men
1.35 (95% CI 1.28-1.43)
Adjusted HR, women vs men
1.19 (95% CI 1.12-1.25)
  • Mortality differences more pronounced in OHCA

ICU mortality, IHCA (subgroup)

Unadjusted HR, women vs men
1.14 (95% CI 1.04-1.25)
Adjusted HR, women vs men (95% CI 0.94-1.13); difference vanished after adjustment
1.03
  • Adjusted for confounders

Interventions before ICU stay

Women received fewer interventions also during ICU stay

Treatment limitations (subgroup, n = 11,202)

Treatment limitations associated with increased risk of death in both sexes

Original publication

Sex disparities in ICU care and outcomes after cardiac arrest: a Swiss nationwide analysis. Crit Care. Published 23 January 2025. doi:10.1186/s13054-025-05262-5

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