Neuroanesthesia & neurocritical care

Long-term survival of traumatic brain injury and intra-cerebral haemorrhage patients: A multicentric observational cohort

J Crit CarePublished Multicentre observational cohort study

Authors' conclusion

In this ICU survivor population with a prolonged follow-up, we highlight an acute risk of death after ICU stay, which seems to last longer in ICH patients. Several variables characteristic of disease severity appeared associated with long-term mortality

Study context

Population
TBI and ICH patients admitted to 3 ICUs from January 2013 to February 2021 and alive at 7 days post-ICU discharge
Participants
435 vs 580
Exposure
ICH vs TBI
  • ICHn = 435
  • TBIn = 580reference
Outcome
Long-term mortality
Methodological details3 ICUs, Lasso-penalized Cox survival analysis
  • 3 ICUs
  • Lasso-penalized Cox survival analysis

Main finding

As reported in the abstract

Survival rate · 7 years

Observational data: associations, not effects.

Further findings

Variables associated with mortality risk

Higher mortality risk with age, ICU LOS, tracheostomy, low GCS, absence of ICP monitoring
Anisocoria related with mortality risk in the early stage after ICU stay

Original publication

Long-term survival of traumatic brain injury and intra-cerebral haemorrhage patients: A multicentric observational cohort. J Crit Care. Published 14 June 2024. doi:10.1016/j.jcrc.2024.154843

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