Lower Limb Ischemia in Surgical Femoral Veno-Arterial Extracorporeal Membrane Oxygenation
Authors' conclusion
Peripheral femoral VA ECMO through a surgical approach is associated with a low LLI rate, which does not increase the risk of in-hospital mortality. The female sex is an independent risk factor for LLI.
Study context
- Population
- Adults receiving surgical peripheral femoral VA ECMO for refractory cardiogenic shock and cardiac arrest, university hospital, 2018–2021
- Participants
- 188 adults
- Exposure
- Lower limb ischemia (LLI) vs no LLI
- LLIn = 12
- Outcome
- Survival to hospital discharge
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
P = 0.571
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Risk factor for LLI: female sex (multivariate)Female sex vs Male sex | 4.38 (1.21–15.81) | P = 0.024 | |
| 0.050.21520Odds ratio (log scale) |
Male sex
P = 0.031
- Incidence of LLI
- 6.4% · 12
- Incidence of LLI — LLI during VA ECMO support
- 6
- Incidence of LLI — LLI after VA ECMO removal
- 6
Original publication
Lower Limb Ischemia in Surgical Femoral Veno-Arterial Extracorporeal Membrane Oxygenation. J Cardiothorac Vasc Anesth. Published 24 July 2023. doi:10. 1053/ j. jvca. 2023. 07. 025
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