Respiratory failure & ventilation
Lung Recruitment Assessed by Electrical Impedance Tomography (RECRUIT): A Multicenter Study of Coronavirus Disease (COVID-19) Acute Respiratory Distress Syndrome
Authors' conclusion
Recruitability varies widely among patients with COVID-19. EIT allows personalizing PEEP setting as a compromise between recruitability and overdistension.
Study context
- Population
- Mechanically ventilated patients with COVID-19 moderate-severe ARDS
- Participants
- 108 participants
- Exposure
- Low vs medium vs high recruiters
- Outcome
- Recruitability (ΔCollapse24-6)
Methodological detailsanalysis of COVID-19 patients from an ongoing study, multicentre
- Analysis of COVID-19 patients from an ongoing study
- Multicentre
Main finding
As reported in the abstract
Recruitability range
0.3% to 66.9%
Observational data: associations, not effects.
Further findings
EIT-based optimal PEEP — Low recruitability vs Medium recruitability · differed between groups
P < 0.05
Positive end-expiratory pressure (PEEP) assigned differently from highest compliance approach
- Patients with different PEEP level vs highest compliance approach
- 81%
Safety
Tolerance of PEEP titration protocol
- Patients not reaching PEEP 24 cm H2O due to hemodynamic instability
- 4
- Protocol well tolerated
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Lung Recruitment Assessed by Electrical Impedance Tomography (RECRUIT): A Multicenter Study of COVID-19 Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. Published 1 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →