ICU sedation, delirium & recovery

Machine Learning for In-hospital Mortality Prediction in Critically Ill Patients With Acute Heart Failure: A Retrospective Analysis Based on the MIMIC-IV Database

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

The XGBoost model can effectively predict the in-hospital mortality of AHF patients admitted to the ICU

Study context

Population
Critically ill intensive care unit (ICU) patients with acute heart failure (AHF), MIMIC-IV database
Participants
5,114 patients
Exposure
XGBoost vs other machine learning (ML) models and common scoring systems
  • Training setn = 3,580
  • Validation setn = 1,534
Outcome
In-hospital mortality prediction
Methodological detailsMIMIC-IV database, machine learning prediction model development and validation, least absolute shrinkage and selection operator (LASSO) variable selection
  • MIMIC-IV database
  • Machine learning prediction model development and validation
  • LASSO variable selection

Main finding

As reported in the abstract

Predictive ability for in-hospital mortality
  • XGBoost had the best predictive ability (AUC) among all ML models and was chosen as final model for higher net benefit
  • XGBoost predictive ability superior to common scoring systems

Observational data: associations, not effects.

Further findings

In-hospital mortality
12.5%

Original publication

Machine Learning for In-hospital Mortality Prediction in Critically Ill Patients With Acute Heart Failure: A Retrospective Analysis Based on the MIMIC-IV Database. J Cardiothorac Vasc Anesth. Published 16 December 2024. doi:10.1053/j.jvca.2024.12.016

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